Beth, from Beth's Blog, (see link) posted today on the MMA list asking for a scan of a
protein electrophoresis with an M- Spike. Since the list won't take attachments, I'll post some of Richard's here.
Serum electropheresis separates the blood proteins into
immunoglobulins and
albumin. MM patients secrete an abnormal immunoglobulin called an
M-protein, m for monoclonal. The amount of M-protein is a measure of disease activity.
Not all myeloma patients have abnormal M protein. Some pateints only secrete abnormal protein into the urine. This is known as
Bence-Jones protein and is quantified with a urine electrophoresis.

Above is Richard's electrophoresis when he was on thalidomide and had no detectable M-spike.

Next is a M-spike of 1.9

Last one is 2.9.
Serum electropheresis separates the blood proteins into immunoglobulins and albumin. MM patients secrete an abnormal immunoglobulin called an M-protein, m for monoclonal. The amount of M-protein is a measure of disease activity.
Not all myeloma patients have abnormal M protein. Some pateints only secrete abnormal protein into the urine. This is known as Bence-Jones protein and is quantified with a urine electrophoresis.
Above is Richard's electrophoresis when he was on thalidomide and had no detectable M-spike.
Next is a M-spike of 1.9
Last one is 2.9.