Research by the University of Wisconsin-Madison has shown that low doses of resveratrol mimic the effects of calorie restriction, which has been shown previously to extend lifespan and reduce the effects of aging.
The researchers examined the influence of resveratrol on heart, muscle, and brain by looking for changes in gene expression in those tissues.
The study compared the genetic crosstalk of animals on a restricted diet with those fed small doses of resveratrol. An example of the results involves gene alterations. The heart has at least 1,029 genes whose functions change with age, and the function of the heart itself is known to weaken with age. From the study, in animals on a restricted diet, 90% of those heart genes experienced altered gene expression profiles, while low doses of resveratrol blocked age-related change in 92%.
The authors state that these findings are associated with prevention of the weakening of the heart associated with aging.
It is also important to note that research done in the past typically used high doses; however, this one shows that the benefits can be obtained with low doses.
I have posted before about the health benefits of resveratrol and how it may be a cancer fighter, but this study provides more evidence to its health benefits. These are interesting results and make me consider taking resveratrol supplements regularly. Unfortunately, I do not like wine, but I probably wouldn’t drink it on a daily basis anyways.
Reference: University of Wisconsin-Madison
Research by the University of Wisconsin-Madison has shown that low doses of resveratrol mimic the effects of calorie restriction, which has been shown previously to extend lifespan and reduce the effects of aging.
The researchers examined the influence of resveratrol on heart, muscle, and brain by looking for changes in gene expression in those tissues.
The study compared the genetic crosstalk of animals on a restricted diet with those fed small doses of resveratrol. An example of the results involves gene alterations. The heart has at least 1,029 genes whose functions change with age, and the function of the heart itself is known to weaken with age. From the study, in animals on a restricted diet, 90% of those heart genes experienced altered gene expression profiles, while low doses of resveratrol blocked age-related change in 92%.
The authors state that these findings are associated with prevention of the weakening of the heart associated with aging.
It is also important to note that research done in the past typically used high doses; however, this one shows that the benefits can be obtained with low doses.
I have posted before about the health benefits of resveratrol and how it may be a cancer fighter, but this study provides more evidence to its health benefits. These are interesting results and make me consider taking resveratrol supplements regularly. Unfortunately, I do not like wine, but I probably wouldn’t drink it on a daily basis anyways.
Reference: University of Wisconsin-Madison