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Claudin-9 Gene Linked to Hearing Loss

Posted Aug 28 2009 7:03pm

Dozens and dozens of genes have been linked to hearing loss, but there are numerous others that are yet to be discovered.   University of Iowa researchers have recently identified claudin-9 as having a connection.  Seems like a "Genes connected to the ear" class is in my future.  Road trip to Iowa City?

"Using a deaf mouse model, the researchers identified the deafness-causing defect in the claudin-9 gene. That mutated gene fails to produce normal claudin-9 protein, which, the University of Iowa team showed, is needed to maintain the proper distribution of potassium in the inner ear."   MORE


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