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Interlukin 2 from the ESPRIT

Posted Feb 10 2009 11:56am
25 countries

2000 patients per arm

Cycles of Subcutaneous il-2 for 5 days 8 days apart

Il 2 increased CD4 cells but provided no improvement in opportunistic infections or death after 8 years

More vascular and psychiatric events with il 2

CD4 cells increased by il 2 may not be functional

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