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MRI in the diagnosis of pediatric multiple sclerosis

Posted Jan 14 2009 8:26pm
Neurology. 2008 Nov 26. [Epub ahead of print]

Summary: MRI diagnostic criteria have not yet been adopted for MS in children. The authors looked for differences in MRI features of MS and other demyelinating diseases and proposed some modifications to the current criteria for adults.

BACKGROUND: MRI diagnostic criteria have not yet been adopted for pediatric multiple sclerosis (MS). MRI plays a pivotal role in supporting the diagnosis of MS in adults. We sought to quantitatively define the MRI features of pediatric MS, to determine features that distinguish MS from nondemyelinating relapsing childhood neurologic disorders, and to propose MRI criteria for lesion dissemination in space in children with MS.

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