
In my layman's terms, you best be prepared to poop yo pants.
From elsewhere:
Alli Side EffectsIn Layman's Terms
Also, consider this, you can promote the growth of COLON CANCER!
The anti-obesity agent Orlistat is associated to increase in
colonic preneoplastic markers in rats treated with a chemical
carcinogen.
Department
of Pathology, Ribeirão Preto Medical School, University of São Paulo,
USP, Avenida Bandeirantes 3900, 14049-900 Ribeirão Preto, SP, Brazil.
sbgarcia@fmrp.usp.br
Orlistat is an anti-obesity
agent that increases the fecal fat excretion, which promotes colon
carcinogenesis. Therefore, the present study was designed to verify the
effects of Orlistat on the formation of rat colonic aberrant crypt foci
(ACF) and cell proliferation evaluated by the PCNA method. Male Wistar
rats received either a standard diet or a high fat diet (HFD),
supplemented or not with Orlistat (200mg/kg chow) and two doses of the
carcinogen dimethyl-hydrazine (25mg/Kg). After 30 days, Orlistat was
associated to a significant increase in the number of colonic ACFs and
cell proliferation in DMH-treated animals, independently of the HFD.

So, you can be thin - if you don't mind losing your bowels and adding to your cancer risk.
In my layman's terms, you best be prepared to poop yo pants.
From elsewhere:
Alli Side EffectsIn Layman's Terms
Also, consider this, you can promote the growth of COLON CANCER!
The anti-obesity agent Orlistat is associated to increase in colonic preneoplastic markers in rats treated with a chemical carcinogen.
Department of Pathology, Ribeirão Preto Medical School, University of São Paulo, USP, Avenida Bandeirantes 3900, 14049-900 Ribeirão Preto, SP, Brazil. sbgarcia@fmrp.usp.br
Orlistat is an anti-obesity agent that increases the fecal fat excretion, which promotes colon carcinogenesis. Therefore, the present study was designed to verify the effects of Orlistat on the formation of rat colonic aberrant crypt foci (ACF) and cell proliferation evaluated by the PCNA method. Male Wistar rats received either a standard diet or a high fat diet (HFD), supplemented or not with Orlistat (200mg/kg chow) and two doses of the carcinogen dimethyl-hydrazine (25mg/Kg). After 30 days, Orlistat was associated to a significant increase in the number of colonic ACFs and cell proliferation in DMH-treated animals, independently of the HFD.
So, you can be thin - if you don't mind losing your bowels and adding to your cancer risk.