What is the effectiveness of using gonadotropin releasing hormone analogues (GnRHa) to treat PMS?
GnRH analogues work to stop menstrual periods by decreasing estrogen production. A recent meta-analysis published in the British Journal of Obstetrics and Gynecology concluded that GnRHa treatment appears to be an effective option in the management of PMS.4 Unfortunately, patients who take these analogues can experience several serious side effects, including menopausal type symptoms such as hot flashes, mood swings, vaginal dryness, and increased LDL cholesterol and bone loss.
GnRH analogues work to stop menstrual periods by decreasing estrogen production. A recent meta-analysis published in the British Journal of Obstetrics and Gynecology concluded that GnRHa treatment appears to be an effective option in the management of PMS.4 Unfortunately, patients who take these analogues can experience several serious side effects, including menopausal type symptoms such as hot flashes, mood swings, vaginal dryness, and increased LDL cholesterol and bone loss.